Ciplukan is a plant that widely used as a traditional medicine e.g : anti-inflammatory, bronchitis, ulcers, cancer, tumors, leukemia and diabetes mellitus due to chemical compounds like saponin , terpenoids, and alkaloids. This research was conducted by making extract ciplukan effervescent tablet using sodium lauryl sulfat, PEG 6000 and sodium benzoate as lubricant. This tablet was made in 3 formula i.e 2% of sodium lauryl sulfat (F1), 3% of PEG 6000 (F2) and 4% of sodium benzoate. The tablet was evaluated for weight uniformity, size uniformity, hardness, friability, dissolve time, and pH’s test. The result shows that the comparison of lubricant can give different in dissolving time. Formula II shows the dissolving time quicker than formula I and formula III. By one way ANOVA analyses with 95% of significance level , among all combinations showed a significant differences.

Magnesium Ascorbyl Phosphate (MAP) is one of derivatives of vitamin C which is more stable in water. MAP hydrophilic nature makes it difficult to penetrate the stratum corneum. Therefore, to increase the penetration, MAP is encapsulated in a liposome system. The sonication can be used to regulated the vesicles size and increase the entrapment efficiency. The purpose of this research was to investigate the effects of sonicator usage time on entrapment efficiency. The thin layer hydration method was used to prepare MAP liposomes with a ratio of lecithin and cholesterol in 30: 1, respectively. The variations of sonicator usage time were 10,15 and 20 minutes. Characterization of liposomes was observed by morphology, vesicle size and drug entrapment studies. The results showed that MAP entrapment efficiency percentage consecutively was 63.4705%; 70.4261%; and 78.0869%; while the size obtained is 466.9 nm; 298.6 nm; and 179.4 nm. One-way ANOVA test results showed a significant difference in each treatment. It can be concluded that the increasing sonicator usage time can decrease vesicle size and increase entrapment efficiency of MAP liposomes. Keywords: Liposomes, Magnesium Ascorbyl Phosphate, Sonication, Sonicator

Probiotics are living microorganisms that can have a positive impact on health when consumed in adequate amounts. This research aimed to determine the effect of different binders on the viability of Lactobacillus acidophilus, a member of Lactic Acid Bacteria (LAB). The probiotic granules were prepared with wet granulation method using mannitol as the filling ingredient. Formulas I-III used acacia as a binder (3%, 4%, and 5%), while Formulas IV-VI used sodium alginate (1%, 1.5%, and 2%). The probiotic granules produced from all formulas were evaluated for flow time, the angle of repose, compressibility, and LAB viability. The LAB viability test results showed that all of the six formulas met the probiotic requirements, i.e., at least 107 CFUs (Colony Forming Units) per gram. The viable LAB in Formulas I-VI were 3.94x107, 4.4x107, 2.7x107, 2.6x107, 3.5x107, and 2.3x107 CFU/g, respectively. The data were analyzed by comparing the average values of the One-Sample T-Test results, followed by Mann-Whitney test. The results revealed that each formula had different capacity in maintaining the viability of Lactobacillus acidophilus with different binders (i.e., acacia and sodium alginate) as a probiotic product. Formula II (4% of acacia) produced probiotic granules that met the requirements of compressibility and the angle of repose. However, its granular flow time exceeded the standard.

Kemampuan naratif merupakan ketrampilan yang berkaitan dengan bahasa ekspresi (expressivelanguage), termasuk bagaimana menggambarkan atau menceritakan berbagai hal, dan termasukmenceritakan kembali (retelling) kisah atau cerita yang sudah didengarkan (storytelling).Dalam kegiatan pembelajaran di Madrasah Muhammadiyah Bandar Lampung, guru menjadikomunikator yang harus memiliki kemampuan ini. Pesan-pesan yang disampaikan baik berupapengetahuan, nilai-nilai, dan nasehat akan mampu diterima dan dipahami dengan baik oleh siswaapabila ditunjang ketrampilan ini. Metode yang dilakukan dalam kegiatan pengabdian meliputiobservasi partisipatoris, dimana tim melakukan pengamatan terhadap kegiatan-kegiatan yangdilakukan oleh mitra, selanjutnya dilakukan diskusi dan wawancara dengan kepala madrasah danguru, dilanjutkan dengan pemaparan materi, feedback, diskusi, sharing pengalaman diikuti denganpraktek, dan terakhir membahas rencana tindak lanjut. Hasil dari kegiatan dapat diidentifikasibahwa menurut para peserta, penguatan guru melalui kegiatan ini dapat dilakukan secara periodikdan berkelanjutan, selain itu guru menjadi termotivasi untuk meningkatkan ketrampilan naratif,termasuk disini adalah peningkatan kemampuan berkomunikasi secara lebih efektif, tepatsasaran, dan berbobot, baik dengan mitra sejawat, orang tua siswa, dan siswa. Selanjutnya paraguru terdorong untuk meningkatkan kemampuannya melalui berbagai perangkat yang dapatmereka akses, misal dengan mengakses internet melalui berbagai media social dan media lainyang terjangkau oleh mereka.