This study aims to identify the importance of implementing Management by Objective (MBO) school extracurricular programs based on the participation of school committees in channeling students' talents and interests by acting right brain functions and developing students' creativity, as well as developing students' psychomotor domains. This study uses framing analysis and analysis of the MBO method, namely SMART. The result of framing analysis is that MBO will succeed, if there is a collaboration arrangement between the school and the school committee based on the school's vision, mission, indicators and objectives, as well as the motto of Jakarta 68 High School is Discipline, creation and achievement. SMART's analysis results are the implementation of extracurricular programs at State Senior High School 68 achieving positive results in developing students' creativity by using psychomotor aspects and the role of school committees based on five dimensions is specific, measurable, acceptable, reality, and time bond.

Purpose of the study: This research aimed to determine the nationalism level of primary education students in the frontier area. Methodology: This research method was quantitative. Data collection was done by distributing questionnaires with nationalism contents. The questionnaire consisted of points that had 12 questions and used a Likert scale. Main Findings: The results of this research implied that border students do not really understand the history of the nation's struggle. In fact, that history can increase patriotism. Border region students must always increase their nationalism because they are the next generation who will guard the land of the frontier area and maintain the honor of the nation. Applications of this study: This research was done in the Sebatik Tengah area which was directly adjacent to Malaysia. Novelty/Originality of this study: The findings showed the lowest of nationalism level of elementary students is to understand the history of the nation's struggle (16%), the spirit of showing national identity (65%), and the spirit of patriotism brings together children on the border area (74%).

Soursop leaves (Annona muricata L.) is one of the medicinal plants identified as a source of endophytic bacteria producing secondary metabolites. Several studies have reported that secondary metabolite compounds extracted from soursop leaves have inhibitory activity against pathogenic bacteria and fungi and have anticancer activity. This study aims to isolate endophytic bacteria of soursop leaf and identify molecular isolates producing antibacterial metabolites by PCR method. This study began with endophytic bacterial isolation of soursop leaves, followed by screening for antibacterial potency using disc diffusion method and identification of molecular isolates which had the highest antibacterial activity. After isolation, three isolates were obtained: BW-1LM, BW-2LP, and BW-3LK. The result of antibacterial activity test showed that BW-1LM isolate had the highest activity against bacterium of Bacillus subtilis and Salmonella typhi test. Molecular identification was obtained by BW-1LW isolate having 99% similarity level to Bacillus licheniformis DSM 13 strain. The conclusion is soursop leaves contains endophytic bacteria which have antibacterial activity against Bacillus subtilis and Salmonella typhi.

Menurut data SUDINKES DKI Jakarta tahun 2016 menunjukkan bahwa kotamadya Jakarta Timur memiliki jumlah populasi yang hipertensi lebih banyak dibandingkan dengan daerah lainnnya yaitu sebanyak 98422 orang. Konsumsi buah dan sayuran segar akan memberikan banyak manfaat bagi tubuh kita, bukan saja rasanya yang enak tapi buah dan sayur kaya akan antioksidan yang bermanfaat untuk mencegah terjadinya stres oksidatif dan bisa menjadi salah satu upaya dalam mencegah dan mengobati hipertensi. Berbagai buah dan sayuran banyak yang telah diteliti memberikan khasiat antihipertensi. Pada pengabdian masyarakat ini kami mengadakan Pelatihan pembuatan nutrisi dan penyuluhan penyakit hipertensi pada anggota PKK RT. 014 Perumnas Klender Jakarta Timur. Buah-buahan dan sayur-sayuran yang kami gunakan adalah belimbing, semangka, lemon, seledri dan mentimun.

Papaya seed in previous research is known has an effect of anthelmintic on Ascardia galli, but the effect of papaya seed just by traditional method i.e. boiling in water. To get the effective extraction methods, it still needs to be done many kinds of extraction methods of papaya seed, to know which one is the best. Methods of extraction in this research were maceration, soxhletation, and ultrasonic digestion. We used two kinds of papaya seed: wet and dry, using solvent: water, 70% ethanol, and n-hexane. Data of anthelmintic activity were percentage of worm death, LD50, and relative potential to pyrantel pamoate as positive control. The result showed that the best extraction method of papaya seed which had highest in vitro effect on Ascardia galli worm was maceration method with 70% ethanol as solvent of wet papaja seed. It killed 60% of worm with LD50 9.36 mg and its relative potential is 0.66 times pyrantel pamoate.

Ekstrak buah mengkudu (Morinda Citrifolia L.) memilki banyak kandungan kimia salah satunya Scopoletin. Namun perbedaan letak geografis suatu tanaman dapat mengakibatkan terjadinya variasi kandungan metabolit dari suatu tanaman. Tujuan penelitian ini untuk mengetahui parameter fisikokimia pada ekstrak etanol 70% buah mengkudu (Morinda Citrifolia L.) dan untuk mengetahui apakah perbedaan daerah tumbuh dapat berpengaruh pada kadar scopoletin pada ekstrak etanol 70% buah mengkudu. Hasil pengujian didapat ekstrak yang berasal dari purwakarta, sari larut air 26,0793 % , sari larut etanol 11,6825 %, kadar abu 1,6517%, kadar abu tidak larut asam 0,3075%, kadar air 11,3014% sedangkan yang berasal dari bogor, sari larut air 42,4098%, sari larut etanol 22,2071%, kadar abu 1,0536%, kadar abu tidak larut asam 0,1001%, kadar air 8,0825%.Pengujian Kadar scopoletin dilakukan dengan metode KLT-Densitometri. KLT menggunakan Fase diam silika gel GF254 dan fase gerak eter: toluen: asam asetat 10% (58:45:0,8). Kadar scopoletin rata-rata daerah Purwakarta adalah 1,4895% dan untuk daerah Bogor adalah 2,4505%. Berdasarkan hasil penelitian mutu ekstrak yang lebih baik adalah buah mengkudu yang berasal dari daerah Bogor dengan nilai parameter non spesifik lebih rendah dan nilai parameter spesifik lebih tinggi.

Reconstructed Human Epidermis (RHE) is an artificial epidermis made in such a way that it resembles human skin, and can be used for the identification of irritant chemicals, especially for cosmetic and topical medicinal products. Currently the new RHE is produced by European and American countries, whose skin physiology is very different from Indonesia. Based on this, the Center for Research on Drugs and Food, NADFC of Republic of Indonesia took the initiative to develop the reconstruction of keratinocyte, melanocytes and fibroblasts cells into RHE adapted to the anatomical and physiological functions of the skin of Indonesians. RHE is made from an epidermal layer composed of keratinocyte and melanocytes cells that are reconstructed with a dermis layer composed of fibroblast and collagen cells. Keratinocyte, melanocytes and fibroblasts cells are cultured on suitable mediums by adding a suitable growth medium. To find out that RHE has been successfully reconstructed, measured percentage of cell life, made histology preparation to see the existence of cell nucleus, and conducted Immunohistochemical examination to see existence of integration (bond) between antigen. From the research results can be seen that keratinocyte cells grown on culture medium Keratinocyte SFM (IX) with rEGF supplements; melanocyte cells grown on Melanocyte 254 culture medium with HMGS supplementation; and fibroblast cells grown on Fibroblast M 106 culture medium with LSGS supplementation. The percentage of epidermal cell life grew well in the planting of 10 � 104 cells /mL keratinocytes and 0.25 � 104 cells /mL of melanocyte cells and survived until the 11th day with live cell percentage of 93.45%. In making preparation for histology with HE staining, there is a cell life in RHE tissue. Used Immunohistochemical (IHC) examination using cytokeratin 10 antibody marker to view physiological function of epidermal tissue.

Insektisida nabati dapat digunakan untuk mengendalikan dan mencegah penyakit yang disebabkan oleh nyamuk. Salah satu alternatif bahan insektisida nabati adalah daun zodia (Evodia suaveolens Scheff.) yang telah dikenal sebagai tanaman pengusir nyamuk. Penelitian ini bertujuan untuk mengetahui efek larvasida dan nilai LC50 dari ekstrak daun zodia terhadap larva nyamuk Aedes albopictus dan Culex spp. Penelitian ini menggunakan ekstrak nheksan daun zodia dengan variasi konsentrasi 10 ppm; 31,62 ppm; 99,98 ppm; 316,13 ppm; 1000 ppm dan kontrol. Metode yang digunakan adalah metode bioassay yang telah distandarisasi oleh WHO (2005). Data hasil penelitian dianalisis menggunakan uji probit. Hasil penelitian menunjukkan bahwa kematian 50% larva nyamuk Aedes albopictus dan Culex spp. (LC50-24 jam) adalah 106,036 ppm dan 116,9110 ppm. Berdasarkan hasil uji probit nilai LC50 masuk ke dalam rentang 100-149 ppm maka dapat disimpulkan bahwa ekstrak n-heksan daun zodia termasuk ke dalam golongan larvasida dengan tingkat toksisitas moderat tinggi.

BACKGROUND Memory is a vital function of the brain. Aerobic exercise has a positive effect on memory’s function, but the appropriate combination of intensity and duration of aerobic exercise is still unknown. This study was aimed to investigate the effect of optimum combinations of intensity and duration of aerobic exercise on spatial memory function.

This study aims to determine the effect of training and work discipline as exogenous factors on employee performance at PT Metro Taruna Jakarta. The 82 respondents as a sample and data analysis and process techniques used are validity, reliability, descriptive analysis, normality test, multicollinearity test, heteroscedasticity test, autocorrelation test, multiple linear regression analysis, simultaneous test, coefficient test, and correlation coefficient of determination. Based on the results of data processing Correlation and Determination Coefficients, the nature of the relationship between training, work discipline and employee performance is affected, because the correlation coefficient is 0.910 and the coefficient of determination r2 = 0.824 or 82.4%, meaning 82.4% variation or change in employee performance variables is the contribution of the influence of training and work discipline variables, while the remaining 17.6% is contributed by the influence of other factors such as compensation, workloads that are not comparable to payments, lack of motivation, high levels of work stress, low levels of promotion and others.